Samson M, Jow MM, Wong CL, Fitzpatrick C, Aslanian A, Saucedo I, Estrada R, Ito T, Park S R, Yates JR and Chu DS

The specification and global reprogramming of histone epigenetic marks during gamete formation and early embryo development in C. elegans

Accepted to PLoS Genetics 


Chu DS and Shakes DC


Adv Exp Med Biol. 2013;757:171-203. doi: 10.1007/978-1-4614-4015-4_7. Review.


Wu JC, Go AC, Samson M, Cintra T, Mirsoian S, Wu TF, Jow MM, Routman EJ, Chu DS

Sperm development and motility are regulated by PP1 phosphatases in Caenorhabditis elegans.

GENETICS 2012 Jan;190(1):143-57. Epub 2011 Oct 31.


Wu TF, Nera B, Chu DS and Shakes DC

Elucidating gene regulatory mechanisms for sperm function through the integration of classical and systems approaches in C. elegans.

Systems Biology in Reproductive Medicine 2010 Jun;56(3):222-35.


Han T, Manorhan AP, Harkins TT, Bouffard P, Fitzpatrick C, Chu DS, Theirry-Mieg D, Thierry-Mieg J, and Kim JK

Germline-generated 26G endo-siRNAs regulate spermatogenic and zygotic gene expression in C. elegans

Proceedings of the National Academy of Sciences 2009 Nov 3;106(44):18674-9.


Shakes DC, Wu J, Sadler PL, LaPrade K, Moore LL, Noritake A and Chu DS

Spermatogenesis-specific features of the meiotic program in Caenorhabditis elegans

PLoS Genetics 2009 Aug;5(8):e1000611. Epub 2009 Aug 21.


Wu, TF and Chu DS

Sperm chromatin: fertile grounds for proteomic discovery of clinical tools.

Mol Cell Proteomics 2008 Oct 7 (10):1876-86.


Wu, TF and Chu DS

Epigenetic processes implemented during spermatogenesis distinguish the paternal pronucleus in the embryo. 

Reproductive BioMedicine Online 2008 Jan;16 (1):13-22.


Chu DS, Liu H, Nix P, Wu TF, Ralston EJ, Yates JR, and Meyer BJ

Sperm chromatin proteomics identifies evolutionarily conserved fertility factors.

Nature 2006 Sep 7, 443 (7107):101-5